Rare DNA Variants and Human Complex Traits: Improving Analyses of Family Studies by Better Modeling the Dependence Structures (Publications).
J. Sun, K. Oualkacha, C. Greenwood and L. Lakhal-Chaieb (10/2017). Multivariate association test for rare variants controlling for cryptic and family relatedness. Canadian Journal of Statistics, special issue featuring the CANSSI CRTs, 32 pages, (under revision). Zhao K, Jiang L, Klein K, Greenwood CMT, Oualkacha K. (11/2017). CpG-set association assessment of lipid concentration changes and DNA methylation on chromosome 11. BMC Proceeding, 6 pages, in press. Jiang L, Zhao K, Klein K, Canty AJ, Oualkacha K, Greenwood CMT. (11/2017). Investigating potential causal relationships between SNPs, DNA methylation and HDL. BMC Proceeding, 6 pages, in press. C. Nieuwoudt (12/2017). R package, SimRVPedigree. Submitted to the Comprehensive R Archive Network (CRAN). J. Sun, K. Oualkacha, C. Greenwood and L. Lakhal-Chaieb (09/2018). Multivariate association test for rare variants controlling for cryptic and family relatedness. Canadian Journal of Statistics, special issue featuring the CANSSI CRTs, 32 pages, (in press). C. Nieuwoudt, S. Jones, A. Brooks-Wilson, and J. Graham (10/2018). Simulating pedigrees ascertained for multiple disease-affected relatives. Source Code for Biology and Medicine, 2018, 13:2. https://doi.org/10.1186/s13029-018-0069-6. Kaiqiong Zhao, Karim Oualkacha, Lajmi Lakhal-Chaieb, Marie Hudson, and Celia MT Greenwood (2019). Smooth modeling of covariate effects in bisulfite sequencing-derived measures of DNA methylation. Paper in progress.